The CBFA2T3-ZNF651 Corepressor Complex: A Potential Drug Target and Biomarker

Target Name: CBFA2T3-ZNF651 corepressor complex

NCBI ID: P17156

CBFA2T3-ZNF651 corepressor complex

Other Name(s): CBFA2T3-ZNF651 complex | CBFA2T3-ZNF651

The CBFA2T3-ZNF651 Corepressor Complex: A Potential Drug Target and Biomarker

The CBFA2T3-ZNF651 corepressor complex is a protein complex that plays a crucial role in regulating gene expression and cell function. The complex is composed of two core transcription factors CBFA2T3 and ZNF651, and is responsible for binding to specific DNA sequences and regulating the activity of downstream target genes. The CBFA2T3-ZNF651 complex is highly conserved across various species, and its membership has been identified in numerous organisms, including humans.

The CBFA2T3-ZNF651 complex is well-established as a gene expression regulator. CBFA2T3 is a corepressor that can bind to multiple DNA sequences with high affinity, while ZNF651 is a co-factor that modulates the binding affinity of CBFA2T3. has been shown to play a role in the regulation of stem cell maintenance, tissue repair, and development.

The CBFA2T3-ZNF651 complex is also a potential drug target. The complex has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Several studies have suggested that disruptions in the CBFA2T3-ZNF651 complex may contribute to the pathogenesis of these diseases. For example, CBFA2T3 has been shown to play a role in the regulation of T cell development and function, while ZNF651 has been implicated in the regulation of neural cell proliferation. Therefore, targeting the CBFA2T3-ZNF651 complex with drugs that can modulate its activity may be a promising strategy for the development of new treatments for these diseases.

The CBFA2T3-ZNF651 complex is also a potential biomarker for disease diagnosis and monitoring. The complex is highly conserved across various species, and its expression levels can be used as a reliable biomarker for the presence of certain diseases. For example, the CBFA2T3-ZNF651 complex has been shown to be downregulated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, measuring the expression levels of the CBFA2T3-ZNF651 complex may be a promising approach for the diagnosis and monitoring of these diseases.

In conclusion, the CBFA2T3-ZNF651 corepressor complex is a protein complex that plays a crucial role in regulating gene expression and cell function. Its membership has been identified in numerous organisms, including humans, and it is a potential drug target and biomarker for various diseases . Further research is needed to fully understand the functions of the CBFA2T3-ZNF651 complex and its potential as a drug target and biomarker.

Protein Name: CBFA2T3-ZNF651 Corepressor Complex

The "CBFA2T3-ZNF651 corepressor complex Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CBFA2T3-ZNF651 corepressor complex comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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